The APMonitor Modeling Language is optimization software for mixed-integer and differential algebraic equations. It is coupled with large-scale solvers for linear, quadratic, nonlinear, and mixed integer programming (LP, QP, NLP, MILP, MINLP). Modes of operation include data reconciliation, real-time optimization, dynamic simulation, and nonlinear predictive control. It is freely available through MATLAB & Simulink or through Python as the Gekko package.