Cell Culture
Apps.CellCultivation History
Show minor edits - Show changes to markup
Deleted lines 16-30:
Sample Results
Input
- (:html:)<a href="/online/plot.php?d=cells&f=MV(1).xml">Substrate Feed Rate</a>(:htmlend:)
Predictions
- (:html:)<a href="/online/plot.php?d=cells&f=SV(1).xml">Cell concentration</a>(:htmlend:)
- (:html:)<a href="/online/plot.php?d=cells&f=SV(2).xml">Substrate concentration</a>(:htmlend:)
- (:html:)<a href="/online/plot.php?d=cells&f=SV(3).xml">Product concentration</a>(:htmlend:)
- (:html:)<a href="/online/plot.php?d=cells&f=SV(4).xml">Oxygen concentration</a>(:htmlend:)
Added lines 1-4:
(:title Cell Culture:) (:keywords nonlinear, model, predictive control, APMonitor, differential, algebraic, modeling language, cell culture:) (:description Simulation of a cell culture with APMonitor:)
Changed lines 20-21 from:
- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=MV(1).xml">Substrate Feed Rate</a>(:htmlend:)
to:
- (:html:)<a href="/online/plot.php?d=cells&f=MV(1).xml">Substrate Feed Rate</a>(:htmlend:)
Changed lines 24-27 from:
- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=SV(1).xml">Cell concentration</a>(:htmlend:)
- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=SV(2).xml">Substrate concentration</a>(:htmlend:)
- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=SV(3).xml">Product concentration</a>(:htmlend:)
- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=SV(4).xml">Oxygen concentration</a>(:htmlend:)
to:
- (:html:)<a href="/online/plot.php?d=cells&f=SV(1).xml">Cell concentration</a>(:htmlend:)
- (:html:)<a href="/online/plot.php?d=cells&f=SV(2).xml">Substrate concentration</a>(:htmlend:)
- (:html:)<a href="/online/plot.php?d=cells&f=SV(3).xml">Product concentration</a>(:htmlend:)
- (:html:)<a href="/online/plot.php?d=cells&f=SV(4).xml">Oxygen concentration</a>(:htmlend:)
Changed line 31 from:
(:html:)<font size=1><pre>
to:
(:html:)<font size=2><pre>
Changed line 31 from:
(:html:)<font size=2><pre>
to:
(:html:)<font size=1><pre>
Changed line 31 from:
(:html:)<pre>
to:
(:html:)<font size=2><pre>
Changed line 79 from:
</pre>(:htmlend:)
to:
</pre></font>(:htmlend:)
Changed lines 27-79 from:
- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=SV(4).xml">Oxygen concentration</a>(:htmlend:)
to:
- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=SV(4).xml">Oxygen concentration</a>(:htmlend:)
(:html:)<pre>
APMonitor Modeling Language
https://www.apmonitor.com
Cultivation of isolated plant cells in suspension culture
Munack A., Posten C. (1989): Design of optimal dynamical experiments for
parameter estimation, Proceedings of the Americal Control Conference,
Vol. 4, 2010-2016.
Model cells
Parameters
romax = 85
yco = 0.897
ypx = 0.0673
vl = 1
kl = 0.0137
os = 86.2
rsmax = 0.0352
ks = 0.186
ko = 6.32
yxs = 5.6
mum = 0.118
rf = 0.05
End Parameters
Variables
x = 4
s = 50
p = 5
o = 0.022
c = 1.059
End Variables
Intermediates
rs = rsmax * s / (ks + s)
mu = yxs*rs - mum
ro = romax * o / (ko + o)
rc = yco*ro
End Intermediates
Equations
$x = mu * x
$s = -rs*x + 10*rf
$p = ypx*mu*x
ro * x = (os - o)*kl*vl
c = rc * x / vl
End Equations
End Model </pre>(:htmlend:)
Changed lines 23-26 from:
- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=SV(4).xml">Oxygen concentration</a>(:htmlend:)
- Product concentration
- Oxygen concentration
to:
- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=SV(4).xml">Oxygen concentration</a>(:htmlend:)
Changed lines 20-21 from:
- Cell concentration
- Substrate concentration
to:
- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=SV(1).xml">Cell concentration</a>(:htmlend:)
- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=SV(2).xml">Substrate concentration</a>(:htmlend:)
- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=SV(3).xml">Product concentration</a>(:htmlend:)
- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=SV(4).xml">Oxygen concentration</a>(:htmlend:)
Changed line 16 from:
- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=MV(1).xml>Substrate Feed Rate</a>"(:htmlend:)
to:
- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=MV(1).xml">Substrate Feed Rate</a>(:htmlend:)
Changed line 16 from:
- Substrate Feed Rate
to:
- (:html:)<a href="https://apmonitor.ath.cx/online/plot.php?d=cells&f=MV(1).xml>Substrate Feed Rate</a>"(:htmlend:)
Changed line 16 from:
- https://apmonitor.ath.cx/online/plot.php?d=cells&f=MV[1].xml|Substrate Feed Rate
to:
- Substrate Feed Rate
Changed line 16 from:
- Substrate Feed Rate
to:
- https://apmonitor.ath.cx/online/plot.php?d=cells&f=MV[1].xml|Substrate Feed Rate
Changed line 16 from:
- Substrate Feed Rate
to:
- Substrate Feed Rate